MOTS-c works by activating the AMP-activated protein kinase (AMPK) pathway, which enhances insulin sensitivity and glucose uptake in skeletal muscle cells. It also promotes mitochondrial biogenesis and function, leading to improved energy metabolism and reduced fat accumulation. Additionally, MOTS-c can translocate to the nucleus under metabolic stress, regulating nuclear gene expression and maintaining cellular homeostasis.
Study on Physical Performance
MOTS-c boosts physical performance.Studies demonstrated that MOTS-c treatment significantly improved running capacity and endurance in mice. Mice treated with MOTS-c ran longer and faster, showing enhanced physical performance and energy metabolism.
Study on Muscle Function
MOTS-c improves muscle function.In dystrophic mice, MOTS-c treatment increased glycolysis and ATP concentration, leading to better muscle function. This suggests that MOTS-c can help improve muscle health and reduce muscle fatigue.
Study on Cardiovascular Health
MOTS-c supports cardiovascular health.Research indicated that MOTS-c improves vascular endothelial function and reduces myocardial damage in diabetic rats. This makes it a promising treatment for cardiovascular complications related to diabetes.
Study on Aging and Longevity
MOTS-c promotes healthy aging.A study found that late-life MOTS-c treatment improved physical capacity and increased median and maximum lifespan in aged mice. This suggests that MOTS-c can help enhance healthspan and reduce age-related physical decline.
Study on Metabolic Flexibility
MOTS-c enhances metabolic flexibility.Research showed that MOTS-c treatment improved the ability of aged mice to switch between using carbohydrates and fats for energy. This metabolic flexibility is crucial for maintaining energy balance and overall health.
Study on Fat Loss and Lean Mass
MOTS-c reduces fat and increases lean mass.A study on breast cancer survivors found that post-exercise MOTS-c levels were associated with reductions in fat mass and increases in lean mass. This indicates that MOTS-c can help improve body composition
Intended Use:
MOTS-c is intended for research purposes only. Reconstitution with bacteriostatic water (BAC water) is required before use.
Storage:
Store lyophilized powder in a cool, dry place away from direct sunlight. After reconstitution, keep refrigerated at 2–8°C.
Solubility:
Reconstitute gently with BAC water. Do not shake.
Vial Size:
Lyophilized multi-dose vial depending on specification.
Shelf Life:
Lyophilized: up to 24 months
Reconstituted: recommended use within 4–6 weeks
Handling:
Use sterile techniques to maintain product stability and integrity.
